In recent years, various assays for molecular typing of microorganisms, e.g. for the purpose of trace-back analyses, have been developed by the Institute. These assays focused on the Bacillus anthracis, Francisella tularensis, Coxiella burnetii, Brucella spp., Burkholderia spp. and Yersinia pestis bacteria. In cooperation with US-American partners the IMB establishe standardized and validated typing methods for bioforensic investigations.
In addition to classical typing techniques, computer-assisted genome analyses are becoming increasingly important. In the medium term, genome sequencing and in silico analyses will largely replace other molecular typing assays. For bioforensic expert reports, where the findings have to be forensically robust, a quality managed validation of the assays and test algorithms is vital.